What can I expect after using the Estradiol Cream?

You will use your product nightly for 2 weeks to replenish estrogen in the vaginal tissues and then will switch to using it nightly twice a week for maintenance. You can note improvement in symptoms such as painful intercourse, vaginal dryness, vulvar irritation, itching, and burning, and reduction in UTIs and UTI symptoms such as urinary frequency. You will see the peak benefits from this treatment at 12 weeks.